Drugs & Vitamins

Septocaine Active Ingredients: Articaine and Epinephrine Representative Names: Septocaine What is articaine-epinephrine injection? What should I tell my health care provider before I take this medicine? How should I use this medicine? What if I miss a dose? What drug(s) may interact with articaine-epinephrine? What side effects may I notice from receiving articaine-epinephrine? What do I need to watch for after I receive articaine-epinephrine? Where can I keep my medicine? What is articaine-epinephrine injection? (Back to top) ARTICAINE-EPINEPHRINE (Septocaine™) is a drug that is injected before and during various dental procedures. Articaine causes loss of feeling in the skin and surrounding tissues. The epinephrine is used to limit the numbing effects of articaine to the intended area. Generic articaine-epinephrine injections are not available. What should I tell my health care provider before I take this medicine? (Back to top) They need to know if you have any of the following conditions: •heart or blood vessel disease •liver disease •myasthenia gravis •an unusual or allergic reaction to articaine, other local anesthetics, or sulfites •pregnant or trying to get pregnant •breast-feeding How should I use this medicine? (Back to top) Articaine-epinephrine is injected into a specific area to make it numb before a dental procedure so you will not feel pain during the procedure. Only a specially trained health-care professional will give articaine-epinephrine in a hospital or clinic. What if I miss a dose? (Back to top) This does not apply. What drug(s) may interact with articaine-epinephrine? (Back to top) •medicines for depression, avoid those called MAO inhibitors (e.g., phenelzine (Nardil®), tranylcypromine (Parnate®), isocarboxazid (Marplan®) •furazolidone •guanadrel •guanethidine •linezolid •medicines for high blood pressure •medicines that improve muscle strength or tone, for conditions like myasthenia gravis •mecamylamine •procarbazine •reserpine Tell your prescriber or health care professional about all other medicines that you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines. What side effects may I notice from receiving articaine-epinephrine? (Back to top) Side effects that you should report to your prescriber or health care professional as soon as possible: •anxiety, restlessness •blurred vision •difficulty breathing •dizziness, drowsiness •irregular heartbeat (palpitations) •nausea, vomiting •seizures (convulsions) •skin rash, itching (hives) •swelling of the face or mouth •tremors If they are going to occur, these side effects may become apparent before you leave the hospital, clinic or dental office. Call your health care provider as soon as you can if you get any of the above reactions later. Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome): •numbness or tingling of the face or mouth •pain at the injection site What do I need to watch for after I receive articaine-epinephrine? (Back to top) Let your prescriber or health care professional know if the feeling of numbness that articaine causes does not wear off within a few hours, or if you find it hard to open your mouth. After an injection of articaine the area will be numb for some time and you will not be aware of pain. Try to avoid injury to the area. Do not chew gum or food until the numbness wears off. You could bite your tongue or the inside of your cheeks. Where can I keep my medicine? (Back to top) You will only receive articaine-epinephrine in a hospital or clinic setting prior to surgery or other procedures. You will not need to take this medicine at home. Last Updated:06/27/2000 CLINICAL PHARMACOLOGY© GOLD STANDARD MULTIMEDIA INC, ALL RIGHTS RESERVED

Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It should not be construed to indicate that the use of the product is safe, appropriate, or effective for you. Consult your healthcare professional before taking the product.